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084f2db8c6 In this model, the fusion of COPII vesicles from the ER begins the formation of the first cis-cisterna of the Golgi stack, which progresses later to become mature TGN cisternae. Cookies are required to use this site. It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach various sugar monomers to proteins as the proteins move through the apparatus. J. PMID18726174. Discovery. These faces are characterized by unique morphology and biochemistry. Within individual stacks are assortments of enzymes responsible for selectively modifying protein cargo. The TGN is the final cisternal structure, from which proteins are packaged into vesicles destined to lysosomes, secretory vesicles, or the cell surface. External links.
Diagram of secretory process from endoplasmic reticulum (orange) to Golgi apparatus (pink magenta). Each compartment has a unique collection of enzymes that work to modify protein cargo. Retrieved 2010-09-20. We are sorry, but an unhandled error occurred. With the development of modern microscopes in the 20th century, the discovery was confirmed. Early references to the Golgi referred to it by various names including the "GolgiHolmgren apparatus", "GolgiHolmgren ducts", and "GolgiKopsch apparatus". The term "Golgi apparatus" was used in 1910 and first appeared in the scientific literature in 1913.. Some doubted the discovery at first, arguing that the appearance of the structure was merely an optical illusion created by the observation technique used by Golgi. This process is known as regulated secretion.